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Immunosuppressive

Immunosuppression is an act of reduction of effectiveness or suppression of immune system. The agents that serve this purpose of suppression of immune system are known as Immunosuppression medication. These medications reduce the risk of rejection of foreign body (like transplanted organ) and inactivate the autoimmune reaction that gets trigger in presence of these foreign bodies. Immunosuppression medications are given at the time of organ transplant to overcome the risk of rejection. These medications are used to treat autoimmune generated diseases such as lupus erythematous, multiple sclerosis, severe allergies, myasthenia gravis and rheumatoid arthritis. Since patient on immunosuppression medication are on compromised immunity they are at a greater risk of infection. Long-term use of immunosuppression medications is associated with development of cancer.       

Two type of immunosuppression medications are:

  • Induction medications: These are potent medications used initially to supress immunity at the time of transplant.
  • Maintenance medications: These medications are used in long run for suppression of immunity. Maintenance immunosuppression medications are further divided into following classes:  
    • Calcineurin Inhibitors: Tacrolimus and Cyclosporine
    • Antiproliferative agents: Mycophenolate Mofetil, Mycophenolate Sodium and Azathioprine
    • Mammalian target of rapamycin (mTOR) inhibitor: Sirolimus
    • Corticosteroids: Prednisone
    • Antibiotics: Polyclonal and monoclonal

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Hepsera Generic

Hepsera Generic

$122.60

Imuran Generic

Imuran Generic

$0.45

Protopic

Protopic

$7.30

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